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. Author manuscript; available in PMC: 2016 Aug 5.
Published in final edited form as: Transplant Direct. 2015 Nov 20;1(10):e44. doi: 10.1097/TXD.0000000000000551

Figure 3.

Figure 3

Functional enrichment analysis of ACR-associated microRNA gene targets. A. Differentially expressed microRNAs in airway epithelium of patients with ACR were linked to 253 experimentally verified gene products, creating a complex interaction network (see also Figure 2). Note that some microRNAs such as miR-34a-5p and miR-124-3p modulated many targets, whereas others influenced very few genes. B. A representative summary of functional categories and pathways enriched among these 253 microRNA-regulated genes reveals that ACR is highlighted by activation of processes involved in proliferation, transformation, development, differentiation, repair, and migration.