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. Author manuscript; available in PMC: 2016 Dec 15.
Published in final edited form as: Cell Mol Gastroenterol Hepatol. 2015 Oct 13;2(1):63–76.e5. doi: 10.1016/j.jcmgh.2015.08.008

Figure 6. Protein expression of p53 and p53-dependent genes and detection of apoptosis in the colorectum of Ugt1F/F and Ugt1ΔIEC mice with colorectal neoplasia following AOM and DSS treatment.

Figure 6

Colorectum tissues from AOM plus DSS-treated Ugt1ΔIEC and Ugt1F/F mice were collected and analyzed. (A) Expression levels of UGT1A, p53, p21, Bax, and cleaved caspase-3 were examined by Western blot analysis with GAPDH as a loading control. Quantitation of the Western blots is shown in Supplemental Figure 4 (B) TUNEL staining of colon sections (100× Magnification). (C) Quantification of the number of TUNEL positive cells.