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. Author manuscript; available in PMC: 2016 Feb 12.
Published in final edited form as: NPJ Schizophr. 2015 Mar 4;1:14001. doi: 10.1038/npjschz.2014.1

Figure 2.

Figure 2

(a) Example of magnetic resonance spectroscopy (1H-MRS) voxel placement in the left substantia nigra (SN; 13 × 13 × 13 mm) overlaid on an axial magnetization transfer contrast image. Insert shows the midbrain without the 1H-MRS voxel. Images are displayed in neurological convention. (b) Sample 1H-MRS spectrum obtained from the left SN; the black line is a spectrum (640 averages), the red line is an overlay of the spectral fit. Cho, choline; Cr, creatine; Glx, glutamate+glutamine; NAA, N-acetyl-aspartate. (c) Glx in the left SN in healthy controls and patients with schizophrenia. Horizontal lines indicate group means.