Skip to main content
. Author manuscript; available in PMC: 2016 Mar 15.
Published in final edited form as: Mol Cell Oncol. 2015 Jun 10;3(1):e1052181. doi: 10.1080/23723556.2015.1052181

Figure 1. Inhibition of guanylate biosynthesis enzymes limits tumor invasion and growth.

Figure 1

Simplified schematic of guanylate metabolic pathway and the proposed model. Enzymes are shown by ovals. Inhibitors of the pathway are indicated. IMP, inositol monophosphate; XMP, xanthosine monophosphate; GMP, guanosine monophosphate; GDP, guanosine diphosphate; GTP, guanosine triphosphate; ATP, adenosine triphosphate; IMPDH, inositol monophosphate dehydrogenase; GMPS, GMP synthase; GMPR, GMP reductase; MPA, mycophenolic acid; MMF, mycophenolate mofetil.