Figure 6. Adoptive transfer of 1,25D3-treated CD8⁺ T cells into CD8-deficient recipients prevents goblet cell metaplasia.

(a–d) Representative photomicrographs of lung histology (original magnification x3200, scale bar 200 μm). (e) Quantitative analysis of PAS-positive goblet cells was determined in cross-sectional areas of the airway wall. Data (mean+SEM) are from two experiments with three mice per experiment. Linear mixed models were employed; pairwise comparisons were performed using t-tests derived from these models. **p<0.01 these p-values remained significant after correction for multiple comparisons; p-values that did not reach the threshold p-value after adjustment for multiple comparisons (Benjamini-Hochberg⁵⁷ correction) are shown numerically.