Table 4.

Testing and Validation of the loratadine/simvastatin interaction using case-only datasets

Data Sets	Odds Ratio	95% CI	N12	N1	N2	N00
INPC CDM	1.53	(1.28, 1.82)	37	1,264	4,197	5,572
FAERS	2.20	(2.02, 3.65)	37	276	6,116	100,531

N12, N1, N2 and N00 is the number of myopathy cases with prescription for both simvastatin and loratadine, simvastatin only, loratadine only, and neither drug, respectively. INPC CDM stands for Indiana Network of Patient Care Common Data Model. FAERS stands for the FDA adverse event reporting system