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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Mol Pharmacol. 2008 Oct 15;75(1):208–217. doi: 10.1124/mol.108.048314

Figure 2.

Figure 2

YC-1 stimulates HO-1 mRNA expression and promoter activity in vascular SMCs. A. Time-course of HO-1 mRNA expression following the administration of YC-1 (50μM). B. Concentration-dependent increase in HO-1 mRNA following the administration of YC-1 (5-100μM for 24 hours). C. Effect of actinomycin D (ActD; 2μg/ml) and cycloheximide (CX; 5μg/ml) on YC-1 (50μM for 8 hours)-mediated increase in HO-1 mRNA. D. Effect of YC-1 (10-100μM for 24 hours) on HO-1 promoter activity. HO-1 mRNA expression is expressed in arbitrary units (a.u.). Results are means ± SEM of 3-5 experiments. *Statistically significant effect of YC-1.