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. Author manuscript; available in PMC: 2016 Dec 15.
Published in final edited form as: Am J Physiol Heart Circ Physiol. 2015 Oct 23;309(12):H2017–H2030. doi: 10.1152/ajpheart.00353.2015

Fig. 4.

Fig. 4

Bcl-2-associated X protein (Bax) and B-cell lymphoma 2 (Bcl-2) protein contents. Relative protein contents of total cell markers of apoptosis from left ventricles of rats exposed by instillation to either vehicle control or PMMTM. Representative immunoblots (top) and densitometric analyses (bottom) for cytosolic Bax (A) and Bcl-2 (B). C: ratio of densitometric analysis of Bax to Bcl-2. Western blots are expressed per GAPDH levels. Immunoblots from coimmunoprecipitation with Bax suggesting the formation of hetero-or homodimers with Bcl-2 (D) or Bax (E). Ratio of densitometric analysis of Bax dimers with Bax to Bcl-2 (F). Values are means ± SE; n = 8 for each group, *P < 0.05 for control vs. exposed.