Fig. 1.

Conceptual model depicting our proposed adolescent neurobiological susceptibility to social context framework, whereby the manner and extent to which social contexts shape developmental outcomes is moderated by adolescents’ neurobiological susceptibility to social context as indexed by brain characteristics (e.g., function, structure). The pink arrows represent the moderated link from social context to developmental outcomes. The blue arrows represent additional bidirectional links among components of the model, which, although important, are not the focus of the proposed framework. Amygdala = AMYG; dorsal anterior cingulate cortex = dACC; dorsolateral prefrontal cortex = dlPFC; hippocampus = HIPP; subgenual anterior cingulate cortex = subACC; ventral prefrontal cortex = vPFC; ventral striatum = VS.