Fig. 3.

Pictorial representation of the brain along with biological factors that have already been established in the literature as neurobiological susceptibility factors. We propose that the brain, on which these other factors converge and from which they derive, is a primary source of neurobiological susceptibility, including of adolescent neurobiological susceptibility. Ultimately, joint consideration of assessments of neurobiological susceptibility factors across multiple levels of analysis may be useful for creating and honing comprehensive, multi-modal profiles regarding which adolescents are likely to experience what outcomes, to the benefit of predictive accuracy and strengthening efforts at prevention and intervention.