Figure 1. Identification of protease inhibitor K11777 as a broad-spectrum antiviral drug candidate.

(a) Structure of K11777; N-methyl-piperazine-phenylalanylhomophenylalanyl-vinylsulfone phenyl. (b) Dose response curves of compound K11777 against pseudoviruses with a variety of different viral envelopes. Data shown as mean ± S.D. of triplicate measurements. Representative experiments of at least three experiments are shown.