Table 4.
Results from SBRS (Range of scores are from 1 to 6 with higher numbers being more abnormal) comparing results from MPS IIIB with MPS IIIA.
| Covariate | MPS IIIB (N=10) |
MPS IIIA (N=8)b |
P-value | MPS IIIBa (N=8) |
P-value |
|---|---|---|---|---|---|
| Movement cluster | 2.2 (0.7) | 2.1 (0.9) | 0.684 | 2.2 (0.8) | 0.766 |
| Lack of fear cluster | 2.3 (0.7) | 2.7 (0.8) | 0.222 | 2.3 (0.7) | 0.261 |
| Social emotional cluster | 2.4 (0.6) | 1.9 (0.6) | 0.151 | 2.3 (0.6) | 0.242 |
| Executive function cluster | 3.6 (1.1) | 3.4 (1.1) | 0.656 | 3.5 (1.2) | 0.861 |
| Unique Domains (not in cluster) | |||||
| Mood, Anger, Aggression | 1.5 (1.0) | 2.1 (1.1) | 0.223 | 1.6 (1.1) | 0.320 |
| Orality | 2.5 (1.4) | 3.1 (1.7) | 0.432 | 2.3 (1.5) | 0.346 |
| Domains of interest (within clusters) | |||||
| Safety Consciousness | 3.1 (1.2) | 3.9 (1.4) | 0.223 | 3.3 (1.2) | 0.349 |
| Emotional function | 2.2 (0.9) | 1.5 (0.9) | 0.132 | 2.1 (0.9) | 0.241 |
| Attention | 4.2 (0.7) | 3.5 (0.6) | 0.030 | 4.2 (0.8) | 0.064 |
| Items of interest (in domains/cluster)** | |||||
| 26. Goes into unsafe areas | 3.4 (1.7) | 5.1 (1.2)1 | 0.027 | 3.2 (1.9) | 0.039 |
| 28. Less fearful | 2.1 (1.5) | 3.6 (1.6) | 0.058 | 2.1 (1.7) | 0.093 |
| 32. Fearful of new people | 1.2 (1.5)2 | 0.2 (0.7) | 0.117 | 1.0 (1.7) | 0.340 |
| 53. Does not pay attention | 3.9 (1.1) | 2.9 (1.2)1 | 0.095 | 3.9 (1.2) | 0.134 |
a
Designates group with 2 outliers (older patients) removed.
b
One patient did not complete the SBRS.
Superscripts denotes number missing.