. Author manuscript; available in PMC: 2016 Feb 9.

Published in final edited form as: AJNR Am J Neuroradiol. 2006 Oct;27(9):1987–1989.

Table.

Discrete lesions identified on diffusion-weighted MR imaging (DWI) and high-resolution DWI (DWI-HR)

	DWI	DWI-HR	P Value
Signal-to-noise ratio, mean (range)	29.7 (23.9–37)	35.6 (27.7–43.2)	<.01
Contrast-to-noise ratio, mean (range)	10.7 (8–17)	14.8 (12.6–20.6)	<.01
Total no. of lesions	129	253	<.001
Average no. of lesions	3.07	6.04	<.001
No. of unique lesions	7	123	<.001
Total lesion volume (mm³)	7040 ± 2010	7052 ± 1950	.95
Average volume per lesion (mm³)	3600 ± 1300	2800 ± 1200	<.001
Average volume per lesion of unique lesions (mm³)	134.41 ± 88.23	70.50 ± 16.90	.65
No. of patients with a single lesions, n (%)	16 (37%)	12 (28%)	n/a
Number of patients with greater than 5 lesions, n (%)	8 (19%)	19 (42%)	n/a

Note:—DWI-HR was acquired following a tetrahedronal encoding scheme with the following gradient directions: (0, 1, 1), (−1, 0, 1), (0, 1, 1), (1, 1, 0), (0, 1, −1), (−1, 1, 0). 100% gradient strength was applied simultaneously along 2 axes affecting a factor of 2 gain in |b|, and allowing for a shorter echo time.