Table 2. List of Differentially expressed proteins among MHO and MAO African-American women determined by label-free serum proteomics.

Accession #	Protein name	Gene symbol	Log effect size (log2FC)	PMHO unadjusted	PMHO BH	Average PC in MHO	Average PC in MAO
8 Under-expressed Proteins in MHO compared to MAO
P69905	Hemoglobin subunit alpha	HBA1	-1.17	3.1×10-21	6.00×10-18	8.5	27.5
P00739	Haptoglobin-related protein	HPR	-0.78	7.6×10-19	1.2×10-15	19.2	42.1
P68871	Hemoglobin subunit beta	HBB	-0.80	4.6×10-15	4.5×10-12	13.8	30.8
P00751	Complement factor B	CFB	-0.21	1.4×10-10	1.1×10-07	172.7	212.6
Q14624	Inter-alpha-trypsin inhibitor heavy chain H4	ITIH4	-0.16	3.0×10-09	1.70×10-06	242	285.1
P02741	C-reactive protein	CRP	-2.13	4.00×10-07	2.0×10-04	1.2	10.1
P27169	Serum paraoxonase1	PON1	-1.16	1.5×10-06	7.0×10-04	2.44	7.8
P0C0L4	Complement C4-A	C4A	-0.081	2.8×10-06	1.0×10-03	638.4	692.5
12 Over-expressed Proteins in MHO compared to MAO
P04114	Apolipoprotein B-100	APOB	0.28	1.9×10-44	1.5×10-40	563.1	423.7
P02765	Alpha-2-HS-glycoprotein	AHSG	0.75	7.7×10-33	3.00×10-29	79.1	37.4
P01008	Antithrombin-III	SERPINC1	0.41	3.50×10-26	9.2×10-23	163.8	108.2
P06727	Apolipoprotein A-IV	APOA4	0.40	8.5×10-18	1.10×10-14	113.8	76.1
P05155	Plasma protease C1 inhibitor	SERPING1	0.71	4.6×10-15	4.5×10-12	37	18.2
P02753	Retinol-binding protein 4	RBP4	0.46	8.1×10-11	7.1×10-08	51.5	32.5
P19823	Inter-alpha-trypsin inhibitor heavy chain H2	ITIH2	0.19	2.3×10-10	1.6×10-07	249.5	206.6
P06396	Gelsolin	GSN	0.25	3.4×10-10	2.25×10-07	135.1	104.3
P04196	Histidine-rich glycoprotein	HRG	0.30	8.9×10-10	5.3×10-07	99.4	73.8
P19827	Inter-alpha-trypsin inhibitor heavy chain H1	ITIH1	0.15	7.5×10-07	0.0004	228.9	196.6
P02774	Vitamin D-binding protein	GC	0.17	1.7×10-06	0.0007	165.8	139.3
P10643	Complement component C7	C7	0.36	1.8×10-05	0.007	34.9	24.4

Cut-off P-value<0.05