Skip to main content
. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Bioessays. 2015 Dec 12;38(1):21–26. doi: 10.1002/bies.201500131

Figure 2. The relationship between frameshift efficiency and mRNA abundance.

Figure 2

The mathematical relationship between 1 PRF efficiency and mRNA abundance was determined using frameshift signals derived from the yeast EST1, EST2, STN1 and CDC13 mRNAs. These were cloned into a reporter gene and cellular mRNA steady-state abundances were plotted relative to the abundance of the reporter without frameshift signals. Plotting of these data fit to the logarithmic function f(x) = e−0.05x (adapted from [22])