Table 1.
CN (N=21) | High likelihood DLB (N=13) | Intermediate likelihood DLB (N=17) | AD (N=18) | X2 | 4-group comparison P-value | |
---|---|---|---|---|---|---|
Median (IQR)/N (%) | Median (IQR)/N (%) | Median (IQR)/N (%) | Median (IQR)/N (%) | |||
Age at blood draw | 81.0 (77.0, 86.0) | 75.5 (73.5, 80.5) | 80.0 (73.0, 86.0) | 78.0 (75.0, 84.0) | 4.82 | .185 |
Age at death | 82.0 (79.0, 90.0) | 78.5 (75.5, 81.5) | 82.0 (74, 88.0) | 82.0 (78.0, 86.0) | 4.07 | .254 |
Men | 16 (76.2%) | 10 (83.3%) | 13 (76.5%) | 13 (72.2%) | 0.50 | .920 |
CDR - final score | 0.0 (0.0, 0.0) | 1.0 (1.0, 1.0)* | 2.0 (1.0, 2.0)*‡ | 2.0 (1.0, 2.0)*† | 46.67 | < .0001 |
MMSE | 29.0 (28.0, 29.0) | 19.0 (18.0, 21.0)* | 15.0 (12.0, 18.0)*‡ | 14.0 (9.0, 17.0)*‡ | 22.87 | < .0001 |
Abbreviations: CN, cognitively normal with normal aging pathology; IQR, interquartile range; DLB, dementia with Lewy Bodies; AD, dementia with Alzheimer’s disease pathology; CDR, Clinical Dementia Rating Scale; MMSE, Mini-Mental State Examination.
P < .01 vs. NC;
P < .01 vs. high likelihood DLB;
P < .05 vs. high likelihood DLB.