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. Author manuscript; available in PMC: 2017 Mar 15.
Published in final edited form as: Clin Infect Dis. 2015 Nov 26;62(6):778–783. doi: 10.1093/cid/civ983

Table 1.

Key Features of the 6 Cases on Onchocerca lupi Infection

Case 1 Case 2 Case 3 Case 4 Case 5 Case 6
Age 22 months old 10 years old 50 years old 13 years old 5 years old 10 years old
Residence Arizona New Mexico Arizona Arizona New Mexico Texas
Location of nodule Cervical spine Scalp Forearm Cervical spine Cervical spine Superior rectus muscle
Additional evaluation for parasites Skin snipsa Eye examb Eye exam Eye exam, lumbar puncture Eye exam, lumbar puncture None
Method of confirming the diagnosis Histology Histology, PCR Histology, PCR Histology Histology Histology, PCR
Histologic findings Gravid adult Nongravid adult Nongravid adult Nongravid adult Gravid adult Multiple nongravid adults
Management Biopsy and ivermectinc Nodule excision Nodule excision, ivermectin, doxycyclined Partial excision, ivermectin, doxycycline Nodule excision, ivermectin, Doxycycline Nodule excision, ivermectin, doxycycline

Abbreviation: PCR, polymerase chain reaction.

a

Skin snips are superficial skin biopsies.

b

Eye exam included a slit lamp examination of the anterior chamber of the eye, which can identify microfilariae.

c

For notes on the use of ivermectin during pregnancy or lactation and in pediatric patients please refer to http://www.cdc.gov/parasites/onchocerciasis/health_professionals/index.html#tx.

d

For notes on the use of doxycycline during pregnancy or lactation and in pediatric patients please refer to http://www.cdc.gov/parasites/onchocerciasis/health_professionals/index.html#tx.