Table 2.
Prehypertensiona | Upper range of prehypertensionb |
Elevated clinic blood pressure diagnostic index using different derived cut-pointsc |
||||||
---|---|---|---|---|---|---|---|---|
≥ 190 mmHg |
≥ 201 mmHg |
≥ 207 mmHg |
≥ 212 mmHg |
≥ 214 mmHg |
≥ 217 mmHg |
|||
N=320 | N=130 | N=572 | N=472 | N=415 | N=351 | N=330 | N=291 | |
Masked daytime hypertension | ||||||||
Sensitivity | 82.5% (113 / 137) |
42.3% (58 / 137) |
98.5% (135 / 137) |
93.4% (128 / 137) |
89.8% (123 / 137) |
81.0% (111 / 137) |
78.8% (108 / 137) |
71.5% (98 / 137) |
Specificity | 61.5% (331 / 538) |
86.6% (466 / 538) |
18.8% (101 / 538) |
36.1% (194 / 538) |
45.7% (246 / 538) |
55.4% (298 / 538) |
58.7% (316 / 538) |
64.1% (345 / 538) |
PPV | 35.3% (113 / 320) |
44.6% (58 / 130) |
23.6% (135 / 572) |
27.1% (128 / 472) |
29.6% (123 / 415) |
31.6% (111 / 351) |
32.7% (108 / 330) |
33.7% (98 / 291) |
NPV | 93.2% (331 / 355) |
85.5% (466 / 545) |
98.1% (101 / 103) |
95.6% (194 / 203) |
94.6% (246 / 260) |
92.0% (298 / 324) |
91.6% (316 / 345) |
89.8% (345 / 384) |
Masked daytime and/or nocturnal hypertensiond | ||||||||
Sensitivity | 71.3% (181 / 254) |
34.3% (87 / 254) |
97.2% (247 / 254) |
90.6% (230 / 254) |
83.9% (213 / 254) |
73.2% (186 / 254) |
71.3% (181 / 254) |
64.6% (164 / 254) |
Specificity | 67.0% (282 / 421) |
89.8% (378 / 421) |
22.8% (96 / 421) |
42.5% (179 / 421) |
52.0% (219 / 421) |
60.8% (256 / 421) |
64.6% (272 / 421) |
69.8% (294 / 421) |
PPV | 56.6% (181 / 320) |
66.9% (87 / 130) |
43.2% (247 / 572) |
48.7% (230 / 472) |
51.3% (213 / 415) |
53.0% (186 / 351) |
54.8% (181 / 330) |
56.4% (164 / 291) |
NPV | 79.4% (282 / 355) |
69.4% (378 / 545) |
93.2% (96 / 103) |
88.2% (179 / 203) |
84.2% (219 / 260) |
79.0% (256 / 324) |
78.8% (272 / 345) |
76.6% (294 / 384) |
PPV: positive predictive value.
NPV: negative predictive value.
Prehypertension: Among adults with non-elevated clinic blood pressure (i.e., systolic blood pressure < 140 mmHg and diastolic blood pressure < 90 mmHg), clinic systolic blood pressure ≥ 120 mmHg and < 140 mmHg or clinic diastolic blood pressure ≥ 80 mmHg and < 90 mmHg.
Upper range of prehypertension: Among adults with non-elevated clinic blood pressure (i.e., systolic blood pressure < 140 mmHg and diastolic blood pressure < 90 mmHg), clinic systolic blood pressure ≥ 130 mmHg and < 140 mmHg or clinic diastolic blood pressure ≥ 85 mmHg and < 90 mmHg.
Clinic blood pressure diagnostic index cut-points associated with 99% (190 mmHg), 95% (201 mmHg), 90% (207 mmHg), 85% (212 mmHg), 80% (214 mmHg), and 75% (217 mmHg) sensitivity.
Masked daytime and/or nocturnal hypertension: Clinic systolic/diastolic blood pressure < 140/90 mmHg and daytime hypertension (i.e., mean daytime systolic blood pressure ≥ 135 mmHg or mean diastolic blood pressure ≥ 85 mmHg) and/or nocturnal hypertension (i.e., mean nighttime systolic blood pressure ≥ 120 mmHg or mean diastolic blood pressure ≥ 70 mmHg).