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Stability and pH-triggered reversibility of the TzB conjugate between 2-FPBA and CAL. a) List of biologically relevant small molecules and their effect (or lack of thereof) on TzB complex formation. b) A collection of 1H-NMR spectra showing the acid-triggered dissociation of the 2-FPBA-CAL conjugate. C) Extent of dissociation of the 2-FPBA-CAL complex under various pH conditions.
