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. Author manuscript; available in PMC: 2015 Jul 15.
Published in final edited form as: Ann Surg Oncol. 2011 Oct 7;19(Suppl 3):S597–S607. doi: 10.1245/s10434-011-2037-0

Figure 6.

Figure 6

Listeria has differential effects on co-receptor expression in tumor bearing mice. a) Listeria does not cause an upregulation of PD-1 expression on CD8+ T-cells. Representative data shown of CD8+ T-cells expressing PD-1 on Day 14 in the liver. b) Total CD8+ T-cell PD-1 expression in the liver and spleen. *p<0.01 NT vs. LMD-AH1, LMD and Naïve in liver on Day 14. c) Total number of CD8+ T-cells expressing the co-receptor CTLA-4 *p<0.05 LMD vs. Naïve in liver and spleen. d) Total number CD4+ T-cells expressing CTLA-4 *p<0.05 LMD vs. LMD-AH1 and NT; **p<0.05 Naïve vs. LMD-AH1, LMD and NT in liver and *p<0.05 LMD-AH1 vs. LMD, NT and Naïve in spleen. N=3 mice per group per day. p= ns unless otherwise noted above.