Skip to main content
. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Mol Oncol. 2016 Apr 29;10(7):1063–1077. doi: 10.1016/j.molonc.2016.04.007

Figure 1. Upregulation of BA in PC condition.

Figure 1

A. The representative box-plot is showing levels of BA in the serum samples obtained from the PC patients (n=36) and healthy (n=10) individuals using a commercially available total BA estimation kit. The difference in BA levels between normal and PC patients were found to be statistically significant. B. To understand the association of BA with PC progression, we measured BA levels in established KPC mice model at early (5-7 wk), medium (10-15 wk) and advanced stages (20-25 wk). The BA levels were found to increase with the severity of the disease. C. Box-plot representing the levels of BA in the pancreatic juice obtained from PC patients. We observed significant increase in BA concentration in the pancreatic juice obtained from PC patients (65 μmol/L) compared to NPNH controls (13 μmol/L). (All values are mean ±S.E, ns means non-significant)