Behavioral training on a visuomotor task. A: Subjects had to move a cursor through a sequence of five targets horizontally arranged on a computer screen (1-Return, 2-Return, 3-Return, 4-Return, 5). B: Pinching a force-transducer with the right hand moved the cursor to the right (i.e., toward a target) whereas releasing pressure moved it back to the left (toward the start position). C: Experimental setup of the 3-session experiment. Day one began with an 8 min resting state scan. Subjects then trained on the visuomotor task outside of the scanner for 30 min. Tests of procedural memory were administered immediately (Immediate), one day (Delayed24h) and 4 weeks (Delayed4wk) after training. D: While at baseline performance between these two groups was comparable, differences between the groups emerged after training at the Immediate, Delayed24h and Delayed4wk tests.