Skip to main content
. Author manuscript; available in PMC: 2010 Feb 1.
Published in final edited form as: Drug Metab Dispos. 2008 Nov 12;37(2):310–314. doi: 10.1124/dmd.108.023531

Figure 2.

Figure 2

Concentration-Effect plots of blood pressure. Each data point represents the mean concentration-effect with the vertical error bar indicating the standard deviation of the measured effect and the horizontal error bar representing the standard deviation in the cocaine plasma concentration. The solid and broken lines are derived from the simple Emax model equation using the mean (n=6) values of Eo, EC50, and Emax for cocaine alone and cocaine + ethanol. The virtually superimposable Emax fits indicate that ethanol does not alter cocaine's concentration-effect relationship.