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. Author manuscript; available in PMC: 2017 Mar 21.
Published in final edited form as: Bone Rep. 2016 Dec;5:141–149. doi: 10.1016/j.bonr.2016.05.002

Figure 3. Femoral bone: Biomechanical properties.

Figure 3

Femoral stiffness and strength were assessed in the 4-point bending assay as described in the Materials and Methods. Data are based on 5 mice at baseline (4 weeks of age), 10 mice at the 5 and 12 month time-points and 15 mice at the 18 month time-point in each group. Values are means and standard deviations. Statistical significance of each parameter was assessed by ANOVA followed by paired group comparisons. Statistical significance at the p<0.05 level is indicated by the letters “a”, “b”, and “c”. The letter “a” above the HFWD + AQ bar indicates statistically significant improvement relative to HFWD alone. The letter “b” above the HFWD + AQ bar indicates statistically significant improvement relative to AIN76A group. The letter “c” above the AIN76A + AQ bar indicates statistically significant improvement relative to AIN76A alone. All of the biomechanical properties measured at the three time points are presented in Supplement Table 5.