Table 2.
Metabolite | Controls | Patients | p-value |
---|---|---|---|
NAA | a8.7±1.2 (n=11) | a8.8±1.6 (n=16) | 0.876 |
Cr | a7.4±1.2 (n=10) | a8.7±2.2 (n=19) | 0.035 |
Cho | a2.1±0.3 (n=10) | a2.3±0.7 (n=18) | 0.189 |
mIns | a5.2±0.9 (n=10) | a6.1±1.5 (n=12) | 0.161 |
Volume (cm3) | 8.4±0.5 (n=11) | 7.5±0.9 (n=19) | 0.003 |
Means ± Standard deviation, number of subjects from whom the data was derived n (in parentheses), and p-values (from unequal variance T tests) of the absolute NAA, Cr, Cho and mIns hippocampal GM concentrations a(millimolar), as well as the volumes of the bilateral hippocampi in controls and patients (in cm3). Significant differences are in boldface; note elevation of Cr and reduction in volume in patients compared to controls.