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. Author manuscript; available in PMC: 2016 Jul 18.
Published in final edited form as: Angew Chem Int Ed Engl. 2016 Jun 3;55(30):8561–8565. doi: 10.1002/anie.201601984

Figure 1.

Figure 1

Performance of MS-Chips for cell separation. A) The complete structure of a mechanical separation chip (MS-Chip) (scale bar: 4 mm). Rectangular microposts are shown with gap widths that decrease from 15 μm to 6 μm (scale bar: 15 μm). B) Fluorescence images of DMSO and Cytochalasin D treated MDA-MB-231 cells trapped in an MS-Chip with a flow rate of 25 μLmin−1. DMSO and Cytochalasin D treated cells were stained with CellTracker Green CMFDA Dye and CellTracker Red CMTPX Dye, respectively (scale bar: 100 μm). C) Comparison of input and output cells in a typical DMSO and Cytochalasin D treated separation of MDA-MB-231 cells with a flow rate of 75 μLmin−1. Both bright-field and fluorescent images are presented (scale bar: 30 μm). D) The proportion of cells after separation in (C) was quantified. Error bars indicate standard error of the mean (SEM; n=3).