Table 1.
Baseline characteristics of participants in the Women's Health Study according to ACE D/I genotype (N=25,000) *
| Characteristic | DD
(N=7,327) |
DI
(N=11,517) |
II
(N=6,156) |
|---|---|---|---|
| Age, mean (SD), y | 54.7 (7.1) | 54.6 (7.1) | 54.8 (7.1) |
| Body mass index, mean (SD), kg/m2 | 25.9 (5.0) | 25.9 (4.9) | 25.9 (4.9) |
| History of diabetes | 2.3 | 2.2 | 2.1 |
| History of hypertension | 25.1 | 24.3 | 24.8 |
| Physical activity | |||
| Never | 36.8 | 37.5 | 36.9 |
| <1/week | 19.4 | 20.0 | 19.4 |
| 1-3/week | 32.3 | 31.3 | 32.1 |
| ≥4/wk | 11.5 | 11.3 | 11.6 |
| Postmenopausal hormone therapy | |||
| Never | 48.1 | 48.0 | 48.6 |
| Past | 9.2 | 9.1 | 8.7 |
| Current | 42.7 | 42.9 | 42.7 |
| History of oral contraceptive use | |||
| No | 30.1 | 29.9 | 30.5 |
| Yes | 69.5 | 69.7 | 69.1 |
| Not sure | 0.4 | 0.4 | 0.5 |
| Alcohol consumption | |||
| Never | 43.1 | 44.2 | 42.4 |
| 1-3 drinks/month | 13.5 | 13.0 | 13.3 |
| 1-6 drinks/week | 32.9 | 32.3 | 33.5 |
| ≥1 drink/day | 10.5 | 10.5 | 10.9 |
| Smoking status | |||
| Never | 50.4 | 51.4 | 51.7 |
| Past | 38.0 | 37.2 | 37.1 |
| Current <15 cigarettes/day | 4.5 | 4.0 | 4.0 |
| Current ≥15 cigarettes/day | 7.1 | 7.4 | 7.3 |
| Family history of MI prior to age 60 yrs | |||
| No | 78.6 | 78.5 | 77.8 |
| Yes | 11.6 | 11.5 | 12.2 |
| Unknown | 9.7 | 10.1 | 10.0 |
*
data are expressed as percentages unless otherwise stated.
Proportions may not add up to 100 due to rounding or missing values.