Table 3.

Multivariable-adjusted^* hazard ratios (HR) and 95% confidence intervals (95% CI) for ischemic vascular events according to ACE D/I polymorphism (n=25,000) assuming an additive mode

	HR	95% CI	p-value
No cardiovascular event (n=24,375) †	1.00	Referent	----
Major Cardiovascular Event (n=625)	0.98	0.88-1.09	0.70
Ischemic Stroke (n=275)	1.03	0.88-1.21	0.70
Myocardial Infarction (n=268)	0.87	0.74-1.02	0.09

^*Controlling for: age, body mass index, diabetes, physical activity, postmenopausal hormone use, oral contraceptive use, history of hypertension, alcohol consumption, smoking categories, and family history of myocardial infarction.

^†The referent group for each of the analyses remained the same and consisted of women without any cardiovascular event during follow-up.