Skip to main content
. Author manuscript; available in PMC: 2017 Feb 7.
Published in final edited form as: J Neurochem. 2016 Aug 15;138(6):806–820. doi: 10.1111/jnc.13718

Figure 3. Lypd6 inhibits nicotine-induced ERK phosphorylation.

Figure 3

(A) Pre-incubation for 10 minutes with 4 μM recombinant human Lypd6 reduces nicotine-induced ERK phosphorylation in PC12 cells, after stimulation with 25 μM nicotine for 5 minutes. (B) Representative images of a western blot membrane summarized in (A), where the phosphorylated isoforms p44 and p42 of the MAP Kinase ERK (ERK1/2) are represented in the top panel (pERK), whereas the total amount of unphosphorylated ERK 1/2 is indicated in the bottom panel (totERK).