Skip to main content
. Author manuscript; available in PMC: 2016 Jul 11.
Published in final edited form as: J Renin Angiotensin Aldosterone Syst. 2016 Jun 9;17(2):10.1177/1470320316652032 1470320316652032. doi: 10.1177/1470320316652032

Figure 1.

Figure 1

The effect of intrarenal renin-angiotensin system (RAS) activity during angiotensin receptor blocker (ARB) treatment on the changes in glomerulotubular sodium (Na) balance by additional treatment with hydrochlorothiazide. In patients, whose intra-renal RAS activity was suppressed during ARB therapy, greater decrease of changes in tubular Na load and tubular Na reabsorption was shown. Intra-renal RAS activity was indicated by daily urinary angiotensinogen excretion. AGT: angiotensinogen; tNa: tubular Na reabsorption (mmol/day); UAGTV: urinary angiotensinogen excretion (log(μg/g Cre)).