Table 1.

Clinical Parameters of Rochester, MN, Men Stratified by Age

	<50 yr	50+ yr	p
Continuous variables are summarized with median (IQR) and a rank sum p value. Categorical variables are summarized with counts (%) and a χ2 p value.
n	125	196
Clinical parameters
Age (yr)	37 (30.8-43.6)	69.8 (60.1-79.6)	—
Height (cm)	179.8 (175.7-183.6)	175 (170-179.5)	<0.001
Weight (kg)	90.5 (79.2-102)	85 (77-95.1)	0.010
Body mass index (kg/m2)	27.7 (25-31.3)	28 (25.8-30.7)	0.874
Calcium intake (mg/d)	1144 (799-1494)	959.7 (732-1308)	0.023
Physically active, n (%)	125 (100)	187 (95)	0.015
Ever smoker, n (%)	40 (32)	108 (55)	<0.001
Current smoking, n (%)	18 (15)	14 (7)	0.032
Former smoking, n (%)	22 (18)	94 (48)	<0.001
Medical history
Hypertension, n (%)	12 (10)	93 (47)	<0.001
Hypercholesterolemia, n (%)	27 (22)	100 (51)	<0.001
Coronary artery disease, n (%)	1 (1)	62 (32)	<0.001
Peripheral vascular disease, n (%)	1 (1)	24 (12)	<0.001
Diabetes mellitus (type 2), n (%)	0 (0)	21 (11)	<0.001
Osteoporotic fracture, n (%)	10 (8)	58 (30)	<0.001
vBMD parameters
Vertebral trabecular (mg/cm3)	179.9 (160.2-200.0)	136.6 (109.2-163.9)	<0.001
Femoral neck
Total (mg/cm3)	337.9 (297.6-363.0)	272.3 (235.1-316.7)	<0.001
Trabecular (mg/cm3)	232.6 (208.0-258.5)	175.7 (149.3-214.1)	<0.001
Cortical (mg/cm3)	569.7 (526.7-619.0)	541.6 (490.1-579.7)	<0.001
Microstructural parameters
Waist			<0.001
BV/TV	0.18 (0.15-0.19)	0.15 (0.13-0.17)
TbN (1/mm)	2.70 (2.48-2.91)	2.79 (2.59-2.94)	0.032
TbTh (mm)	0.06 (0.06-0.07)	0.06 (0.05-0.06)	<0.001
TbSp (mm)	0.31 (0.28-0.33)	0.30 (0.29-0.33)	0.988
Aortic calcification	0.26 (0.04-1.17)	38.13 (5.11-119.24)	<0.001
(Agatston score per CT slice)
Agatston score > 0, n (%)	95 (76)	190 (97)	<0.001