Table 6.

Unadjusted/Univariate-Adjusted/Multivariable-Adjusted Spearman Correlation Coefficients Between Hormonal Variables, Bone Formation Markers, and Bone Resorption Markers With Aortic Calcification per 2.5-mm CT Slice in Rochester, Minnesota, Women Combined and Stratified by Menopausal Status

	All women			Premenopausal			Postmenopausal
	U	A	A/B/C	U	A	A/B/C	U	A	A/B/C
U, unadjusted; A, age adjusted; A/B/C, age, BMI, cigarette smoking status (ever) adjusted.
Hormonal variables
Bio E2 (pg/ml)	-0.49*	0.13	0.08	0.23†	0.22†	0.12	-0.17†	0.06	0.09
Bio T (ng/dl)	0.04	0.22*	0.16†	0.32‡	0.42*	0.21	-0.07	0.10	0.12
PTH (pM)	0.12	-0.00	-0.05	0.14	0.09	-0.06	-0.02	-0.03	-0.02
25-Hydroxyvitamin D (ng/ml)	-0.17‡	-0.19‡	-0.16†	-0.19	-0.21	-0.17	-0.14	-0.17†	-0.18†
1,25-Dihydroxy vitamin D (pg/ml)	-0.20‡	-0.09	-0.07	-0.07	-0.11	-0.04	-0.15	-0.11	-0.12
IGF-1 (ng/ml)	-0.42*	-0.09	-0.07	-0.30‡	-0.16	-0.09	-0.29*	-0.13	-0.12
IGFBP-3 (ng/ml)	-0.14†	0.07	0.07	-0.05	0.03	0.04	-0.14	0.01	0.03
Bone formation markers
Bone alkaline phosphatase (U/liter)	0.37*	0.21‡	0.19‡	0.31‡	0.35‡	0.24†	0.11	0.11	0.12
Osteocalcin (ng/ml)	0.07	-0.03	0.02	-0.24†	-0.12	-0.08	-0.02	-0.00	0.02
PINP (jig/liter)	-0.01	0.01	0.02	-0.09	0.01	0.03	-0.14	0.02	0.01
Bone resorption markers
Serum CTX (ng/ml)	0.13†	-0.03	0.00	-0.14	-0.05	-0.04	-0.05	-0.01	-0.01
Urine NTX (nM GF)	0.20‡	0.02	0.03	0.04	0.09	-0.02	0.01	0.02	0.03

^*p < 0.001.

^†p < 0.05.

^‡p < 0.01.