(a) Progression-free survival curves comparing those patients not receiving IFN-α-2b (Cohort 0) to those receiving any dose of IFN-α-2b (Cohorts 1–4). (b) Overall survival curves comparing those patients not receiving IFN-α-2b (cohort 0) to those receiving any dose of IFN-α-2b (Cohorts1–4) (c) Progression-free survival curves and (d) overall survival curves comparing all 5 study arms: Cohort 0, no IFN-α-2b; Cohort 1, IFN-α-2b (1×106 U); Cohort 2, IFN-α-2b (3×106 U); Cohort 3, IFN-α-2b (6×106 U); Cohort 4, IFN-α-2b (9×106 U)