Table 4. NGS analysis of the HSV1m8 target site in HSV genomes.
Mouse identification number | Treatment | % mutation | % deletions | % insertions |
---|---|---|---|---|
1 | PBS | 0.16 | 0.08 | 0.08 |
2 | NV1/Trex2 | 0.16 | 0.09 | 0.07 |
7 | HSV1m8/Trex2 | 0.32 | 0.24 | 0.08 |
8 | HSV1m8/Trex2 | 1.27 | 1.07 | 0.20 |
9 | HSV1m8/Trex2 | 1.04 | 0.71 | 0.33 |
10 | HSV1m8/Trex2 | 1.82 | 1.60 | 0.22 |