Table 4.
Ordinal regression models using the severity of CIPN-sx to predict perceived work ability in chemotherapy-treated (Ctx+) breast cancer survivors approximately 1 month after treatment (N = 22)
| Variable (reference) | Coefficient | SE | Wald | p value | 95 % CI |
Cumulative odds ratio | Nagelkerke r2 | |
|---|---|---|---|---|---|---|---|---|
| Lower | Upper | |||||||
| Combination 1, hand symptoms | ||||||||
| Ability to work (not at all) | −4.24 | 1.26 | 11.39 | 0.001 | −6.70 | −1.78 | 0.008 | 0.500 |
| Hand numbness (somewhat) | −4.50 | 1.89 | 5.64 | 0.018 | −8.21 | −.786 | ||
| Trouble feeling the shape of small objects (very much) | 7.28 | 3.13 | 5.43 | 0.020 | 1.16 | 13.41 | ||
| Combination 2, hand symptoms | ||||||||
| Ability to work (not at all) | −5.50 | 1.53 | 12.99 | 0.000 | −8.50 | −2.51 | 0.004 | 0.567 |
| Trouble buttoning buttons (a little bit) | −3.79 | 1.60 | 5.60 | 0.018 | −6.93 | −0.65 | ||
| Trouble feeling the shape of small objects (somewhat) | −4.48 | 1.87 | 5.75 | 0.017 | −8.15 | −0.82 | ||
| Combination 3, lower extremity | ||||||||
| Ability to work (not at all) | −3.47 | 1.26 | 7.65 | 0.006 | −5.94 | −1.01 | 0.031 | 0.644 |
| Foot numbness (somewhat) | −5.98 | 2.36 | 6.40 | 0.011 | −10.6 | −1.35 | ||
| Foot pain (quite a bit) | 9.36 | 4.21 | 4.95 | 0.026 | 1.12 | 17.60 | ||
| Combination 4, lower extremity | ||||||||
| Ability to work (not at all) | −5.79 | 1.77 | 10.67 | 0.001 | −9.26 | −2.32 | 0.003 | 0.724 |
| Foot numbness (quite a bit) | −4.68 | 1.83 | 6.52 | 0.011 | −8.28 | −1.09 | ||
| Trouble walking (quite a bit) | 4.40 | 2.12 | 4.33 | 0.037 | 0.26 | 8.55 | ||
| Combination 5, hearing and hand pain | ||||||||
| Ability to work (not at all) | −5.32 | 1.54 | 12.02 | 0.001 | −8.33 | −2.31 | 0.005 | 0.583 |
| Hand pain (very much) | −3.94 | 1.72 | 5.26 | 0.022 | −7.32 | −0.57 | ||
| Trouble hearing (a little bit) | −4.31 | 1.85 | 5.45 | 0.020 | −7.94 | −0.69 | ||
Values represent the results of separate univariate ordinal regression models using the severity of individual CIPN-sx as predictor variables and self-reported ability to work (including housework) as the dependent variable (categories: not at all, a little bit, somewhat, quite a bit, very much). To ensure that models predicted poor work performance based on the severity CIPN-sx, CIPN-sx were reverse coded (i.e., 0 = very much, 1 = quite a bit, 2 = somewhat, 3 = a little bit, 4 = not at all). Note Values in italics are significant at α= 0.05
SE standard error, CI confidence interval