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. Author manuscript; available in PMC: 2016 Dec 2.
Published in final edited form as: Ann Neurol. 2016 Oct 19;80(5):730–740. doi: 10.1002/ana.24780

Table 2.

Replication populations

Variable MGH ERICH University of
Brescia
UMC Utrecht University of
Edinburgh
Case Ctrl Case Ctrl Case Ctrl Case Ctrl Case Ctrl
n 240 458 920 826 198 185 157 160 110 216
Age, n (SD) 76
(10)
69
(11)
69
(14)
68
(13)
69
(13)
63
(14)
62
(13)
56
(11)
75 (9) 76
(10)
Female, n
(%)
96
(40)
206
(45)
397
(43)
371
(45)
81
(41)
85
(46)
66
(42)
67
(42)
59
(54)
118
(54)
Lobar , n (%) 120
(48)
- 380
(41)
- 82
(41)
- 60
(38)
- 61
(55)
-
Genotyping
platform
iPLEX iPLEX Taq-
man
Taq-
man
iPLEX iPLEX iPLEX iPLEX iPLEX iPLEX
Replication
Totals
3470 individuals (1625 cases, 1845 controls), 42% lobar ICH
Discovery +
Replication
Totals
5625 individuals (2595 cases, 3030 controls), 45% lobar ICH

Abbreviations: Ctrl = Control; ERICH = Ethnic/Racial Variations of Intracerebral Hemorrhage; iPLEX = Sequenom MassARRAY iPLEX Platform; MGH = Massachusetts General Hospital; TaqMan = Applied Biosystems Taqman Genotyping Assay