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. Author manuscript; available in PMC: 2016 Dec 2.
Published in final edited form as: Ann Neurol. 2016 Oct 19;80(5):730–740. doi: 10.1002/ana.24780

Table 5.

Replication results for SNPs in LD with rs173539 and meta-analysis of all samples

Replication Discovery/Replication
Meta-analysis
SNP Effect OR SE p I2 Effect OR SE p I2
rs247617 +++++ 1.08 0.05 0.18 2 +++/+++++ 1.13 0.04 1.0×10−3 0
rs17231506 +++++ 1.08 0.05 0.17 1 +++/+++++ 1.13 0.04 1.0×10−3 0
rs711752 ++++− 1.12 0.05 0.03 7 ++−/++++− 1.13 0.04 1.0×10−3 0
rs708272 ++++− 1.14 0.05 0.01 4 ++−/++++− 1.14 0.04 5.0×10−4 0

OR = odds ratio, SE = standard error, SNP = single nucleotide polymorphism, + = variant increases ICH risk, − = variant decreases ICH risk.