Table 3.
DHFR Species Ligand | Residue Cα 30-22 | Residue Cα 30...21 | Residue Cα 30...59 | Residue Cα 30...60 |
---|---|---|---|---|
m-PT684a | 12.2Ǻ | 15.1Ǻ | 17.5Ǻ | 15.3Ǻ |
m-holo | 12.3 | 15.3 | 17.2 | 15.3 |
mL22R-MTX Cody et al, 2005 | 12.1 | 14.5 | 16.5 | 14.8 |
h-MTX Cody et al, 2005 | 12.2 | 14.7 | 16.2 | 14.6 |
pc-PT653 Cody et al, 2002 | 12.3 | 15.1 | 17.9 | 15.9 |
pc-MTX Cody et al, 1999 | 11.7 | 15.0 | 16.5 | 14.7 |