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. Author manuscript; available in PMC: 2009 Jan 8.
Published in final edited form as: Acta Crystallogr D Biol Crystallogr. 2008 Aug 13;64(Pt 9):977–984. doi: 10.1107/S0907444908022348

Table 3.

Contact distances between active site residues for DHFR complexes

DHFR Species Ligand Residue Cα 30-22 Residue Cα 30...21 Residue Cα 30...59 Residue Cα 30...60
m-PT684a 12.2Ǻ 15.1Ǻ 17.5Ǻ 15.3Ǻ
m-holo 12.3 15.3 17.2 15.3
mL22R-MTX Cody et al, 2005 12.1 14.5 16.5 14.8
h-MTX Cody et al, 2005 12.2 14.7 16.2 14.6
pc-PT653 Cody et al, 2002 12.3 15.1 17.9 15.9
pc-MTX Cody et al, 1999 11.7 15.0 16.5 14.7