Table 4.
Timepoints | Estimated change ± SE and % change | ||||||||
---|---|---|---|---|---|---|---|---|---|
0 | 6 mo | 12 mo | 0–6 mo | % | 6–12 mo | % | 0–12 mo | % | |
Trabecular vBMD |
224.1 | 211.0 | 203.0 | −13±12.9 | −5.8 | −7.6 ±13.6 | −3.6 | −20.6 ±21.1 | −9.2 |
Trabecular CSA |
206.8 | 196.0 | 175.0 | −10.5±42.7 | −5.1 | −21.1±45.0 | −10.8 | −31.7±69.9 | −15.3 |
Cortical vBMD |
1143.5 | 1146.0 | 1151.0 | 2.4±23.7 | 0.2 | 4.7±24.7 | 0.4 | 7.1±37.3 | 0.6 |
Cortical CSA |
68.5 | 64.0 | 65.0 | −4.7±1.5a | −6.8a | 0.9±1.6 | 1.3 | −3.8±2.4 | −5.6 |
Cortical BMC |
79.1 | 73.8 | 74.8 | −5.3±1.8a | −6.7a | 1.1±1.9 | 1.4 | −4.2±2.9 | −5.4 |
Cortical thickness |
2.92 | 2.78 | 2.80 | −0.14±0.05a | −4.8a | 0.02±0.05 | 0.7 | −0.12±0.08 | −4.1 |
BSI | 31.8 | 27.0 | 26.0 | −4.3±1.9a | −13.6a | −1.2±1.9 | −4.2 | −5.5±3.1 | −17.2 |
Zp | 186.7 | 179.0 | 180.0 | −7.3±5.6 | −3.9 | 0.2±5.9 | 0.1 | −7.1±8.8 | −3.8 |
SSI | 154.7 | 154.0 | 156.0 | −0.2±5.2 | −0.1 | 1.9±5.8 | 1.2 | 1.6±8.2 | 1.0 |
Data are shown as adjusted means for the radius length, estimated change ± SE, and percent change;
significant change, P<0.05. BMC, bone mineral content (mg/mm); BSI, bone strength index is expressed in mg2/mm4; cortical thickness is expressed in mm; CSA, cross-sectional area (mm2); vBMD, volumetric bone mineral density (mg/cm3); Zp, polar section modulus and SSI, strength strain index are expressed in mm3.