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. Author manuscript; available in PMC: 2017 Apr 6.
Published in final edited form as: Anat Rec (Hoboken). 2017 Jan 11;300(3):560–576. doi: 10.1002/ar.23511

Figure 6.

Figure 6

Morphometric differences in components of the glomerular filtration barrier in 150 day old FVB, JTMT, OVE and OVE- JTMT mice. A. Mean percent non-fenestrated endothelium ± S.D: FVB vs. OVE, JTMT vs. OVE, and OVE-JTMT vs. OVE all show statistically significant differences. OVE mice show greatest percentage of non-fenestrated endothelium, while OVE-JTMT mice exhibited significant protection against non-fenestration. B. Mean glomerular basement membrane thickness ± S.D: FVB vs. OVE, JTMT vs. OVE, and OVE-JTMT vs. OVE all show statistically significant differences. OVE mice show the thickest glomerular basement membrane, while OVE-JTMT mice show complete elimination of basement membrane thickening. C. Mean podocyte foot process width ± S.D: FVB vs. OVE, JTMT vs. OVE, and OVE-JTMT vs. OVE all show statistically significant differences. OVE mice show the widest foot processes (greatest foot process effacement) while OVE-JTMT mice show significant protection against increased foot process width.