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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Antiviral Res. 2016 Nov 8;137:1–5. doi: 10.1016/j.antiviral.2016.11.002

Table 3.

Human viral diseases which researchers have failed to recapitulate through experimental inoculation of laboratory primates, suggesting that the virus may need to be propagated in its natural reservoir or in a vector species to remain pathogenic.

Disease Etiological agent Reservoir or host
Hemorrhagic fever
with renal syndrome		 Hantaan and
Dobrava viruses		 Rodents (e.g. Apodemus species)
Crimean-Congo
hemorrhagic fever
(CCHF)		 CCHF virus Ruminants, Hyalomma species
ticks
Lujo hemorrhagic
fever		 Lujo virus Unknown
Severe-acute
respiratory syndrome
(SARS)		 SARS
coronavirus		 Bats
Dengue hemorrhagic
fever		 Dengue virus Aedes mosquitos
Severe fever with
thrombocytopenia
(SFTS)		 SFTS virus Haemaphysalis ticks