TABLE I.

The mean and standard deviation of Dice ratios of the combined WM and GM for intra-subject registration, by aligning the 2-week-old, 3-, 6-, and 9-month-old images to the 12-month-old image via different methods. The best Dice ratio for each column is shown in bold.

Method	2-week to 12-month	3-month to 12-month	6-month to 12-month	9-month to 12-month
CC-based	0.714 ± 0.025	0.687 ± 0.031	0.797 ± 0.028	0.851 ± 0.019
MI-based	0.709 ± 0.028	0.694 ± 0.030	0.799 ± 0.029	0.850 ± 0.018
3D-HAMMER	0.764 ± 0.027	0.756 ± 0.028	0.806 ± 0.024	0.848 ± 0.021
SR-based	0.774 ± 0.015	0.778 ± 0.018	0.818 ± 0.016	0.858 ± 0.015
Our proposed method1	0.810 ± 0.044	0.783 ± 0.054	0.823 ± 0.056	0.892 ± 0.009
Our proposed method2	0.833 ± 0.029	0.826 ± 0.026	0.847 ± 0.041	0.892 ± 0.006