TABLE III.

The mean and standard deviation of Dice ratios of the combined WM and GM for inter-subject registration, by aligning 2-week-old, 3-, 6-, and 9-month-old images to the 12-month-old image via different methods. The best Dice ratio for each column is shown in bold.

Method	2-week to 12-month	3-month to 12-month	6-month to 12-month	9-month to 12-month
CC-based	0.643 ± 0.030	0.618 ± 0.025	0.684 ± 0.024	0.722 ± 0.020
MI-based	0.614 ± 0.025	0.602 ± 0.022	0.675 ± 0.030	0.717 ± 0.022
3D-HAMMER	0.662 ± 0.023	0.642 ± 0.026	0.688 ± 0.025	0.715 ± 0.023
SR-based	0.673 ± 0.016	0.665 ± 0.017	0.695 ± 0.015	0.718 ± 0.018
Our proposed method 1	0.623 ± 0.029	0.633 ± 0.026	0.661 ± 0.050	0.676 ± 0.039
Our proposed method 2	0.692 ± 0.035	0.684 ± 0.037	0.726 ± 0.069	0.766 ± 0.033