Table 1.

Expression of IgE binding structures on hematopoietic or non- hematopoietic cells in humans.

IgE binding structure	Receptor composition/splice variants	Expression on hematopoietic cells	Expression on non-hematopoietic cells
High affinity IgE receptor/FcεRI	Tetrameric receptor αβγ2	Mast cells, basophils Kraft S, Kinet JP. Nat Rev Immunol. 2007 May;7(5):365–78.	-
	Trimeric receptor αγ2	Mast cells, basophils Kraft S, Kinet JP. Nat Rev Immunol. 2007;7(5):365–78. Monocytes, macrophages Boltz-Nitulescu G, et al. Monogr Allergy. 1983;18:160–2. Spiegelberg HL. Int Rev Immunol. 1987;2(1):63–74. Dendritic cells Novak N, et al. J Clin Invest. 2003; 111(7):1047–56. Bieber T, et al. J Exp Med. 1992; 175(5):1285–90. Allam JP, et al. J Allergy Clin Immunol. 2003; 112(1):141–8. Bannert C, et al. PLoS One. 2012; 7(7):e42066. Yen EH, et al. J Pediatr Gastroenterol Nutr. 2010; 51(5):584–92. Eosinophils Gounni AS et al. Nature. 1994, 367(6459):183–6. Platelets Hasegawa S et al. Blood. 1999; 93(8):2543–51.	Small intestinal and colonic epithelial cells Untersmayr et al. PLoS One. 2010 Feb 2;5(2):e9023.
	α chain	Neutrophils Dehlink et al, PLoS One. 2010, 5(8):e12204. Alphonse MP et al. PLOS one 2008; 3(4):e1921	Paneth cells Untersmayr E et al. PLoS One. 2010;5(2):e9023. Smooth muscle cells Gounni AS et al. J Immunol. 2005;175(4):2613–21.
Low affinity IgE receptor/FcεRII/CD23	CD23a isoform	Antigen-activated B cells Reviewed in: Gould HJ, Sutton BJ. Nat Rev Immunol. 2008;8(3):205–17. doi: 10.1038/nri2273.
	CD23b isoform	B cells Yukawa K, et al. J Immunol. 1987;138(8):2576–80. Monocytes, macrophages Vercelli D et al. J Exp Med. 1988;167(4):1406–16. Pforte A et al. J Exp Med. 1990;171(4):1163–9. Eosinophils Capron M et al. Chem Immunol. 1989;47:128–78. Platelets Capron M et al. J Exp Med. 1986;164(1):72–89. Dendritic cells Bieber T et al. J Exp Med. 1989;170(1):309–14.	Small intestinal and colonic epithelial cells Kaiserlian D et al. Immunology. 1993 Sep;80(1):90–5.
Galectins	Galectin 3	Monocytes, macrophages Liu FT et al. Am J Pathol. 1995;147(4):1016–28. Neutrophils Truong MJ, et al. J Exp Med. 1993;177(1):243–8. Eosinophils Truong MJ et al. Eur J Immunol. 1993;23(12):3230–5. Basophils and mast cells Craig SS et al. Anat Rec. 1995;242(2):211–9. Dendritic cells Brustmann H. Int J Gynecol Pathol. 2006;25(1):30–7. Smetana K et al. J Leukoc Biol. 1999;66(4):644–9.	Gastric cells Fowler M et al. Cell Microbiol. 2006;8(1):44–54. Small intestinal, colonic, corneal, conjunctival and olfactory epithelial cells, epithelial cells of kidney, lung, thymus, breast, prostate Dumic J, et al. Biochim Biophys Acta. 2006;1760(4):616–35. Jensen-Jarolim E et al. Eur. J. of Gastroenterology & Hepatol. 2002;14(2):145–52. Uterine epithelial cells von Wolff M et al. Mol Hum Reprod. 2005;11(3):189–94. Fibroblasts Openo KP et al. Exp Cell Res. 2000;255(2):278–90. Chondrocytes and osteoblasts Janelle-Montcalm A et al. Arthritis Res Ther. 2007;9(1):R20. Osteoclasts Nakajima K et al. Cancer Res. 2016;76(6):1391–402. Keratinocytes Konstantinov KN et al. Exp Dermatol. 1994;3(1):9–16. Neural cells Pesheva P et al. J Neurosci Res. 1998; 54(5):639–54.
	Galectin 9	T-cells Chabot S et al. Glycobiology. 2002 Feb;12(2):111–8. Monocytic cells, macrophages Harwood NM et al. J Leukoc Biol. 2016; 99(3):495–503. Mast cells Wiener Z et al. J Invest Dermatol. 2007; 127(4):906–14.	Intestinal epithelial cells Chen X et al. Allergy. 2011;66(8):1038–46. M-cells Pielage JF et al. Int J Biochem Cell Biol. 2007;39(10):1886–901. Nasal polyp fibroblasts Park WS et al. Biochem Biophys Res Commun. 2011;411(2):259–64. Endometrial epithelial cells Shimizu Y et al. Endocr J. 2008;55(5):879–87. Endothelial cells Imaizumi T et al. J Leukoc Biol. 2002; 72(3):486–91.