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. Author manuscript; available in PMC: 2017 Feb 28.
Published in final edited form as: J Cell Physiol. 2016 May 8;231(11):2529–2540. doi: 10.1002/jcp.25407

Fig. 4.

Fig. 4

Altered microbiota composition in SHP-2IEC-KO mice. Taxonomic microbiota composition at phylum level in SHP- 2IEC-KO and control littermates at the age of 4 days (A), 2 weeks (B), and 1 month (C) was determined by deep sequencing analysis. PCoA ordination plot constructed on the Bray Curtis distance matrix calculated on normalized data from SHP-2IEC-KO and control littermates at the age of 2 weeks (D) and 1 month (E). Alpha-diversity (within community) measures (richness, measured as observed species and diversity measured as Shannon’s diversity index) in SHP- 2IEC-KO and control littermates at the age of 2 weeks (F) and 1 month (G). (H) Changes at genus level in SHP-2IEC-KO and control littermates at the age of 2 weeks and 1 month (n ≥ 7 per group). *P ≤ 0.05. The error bars indicate SEM.