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. Author manuscript; available in PMC: 2009 Sep 15.
Published in final edited form as: J Neurosci. 2008 Dec 24;28(52):14156–14164. doi: 10.1523/JNEUROSCI.4147-08.2008

Figure 2.

Figure 2

Decrease in the number of microglial processes around amyloid deposition. The number of processes extending from the cell body were counted in areas containing CAA, parenchymal amyloid plaques, and no amyloid pathology (no path). Microglia were compared in 14–17 month old mice around CAA, parenchymal amyloid plaques, and in areas with no amyloid pathology as well as in 3 ½ – 6 ½ month old PDAPP+/−;CX3CR1/GFP+/− mice lacking amyloid pathology and 5 month old PDAPP−/−;CX3CR1/GFP+/− mice. Five mice were studied per age group in APP transgenic mice and 6 fields of view were imaged in each animal. Six fields of view were studied in 2 non-APP transgenic mice. Data is presented as mean +/− SEM. * p<0.001.