Table 2.
Multivariable-adjusted hemodynamic correlates of brachial and carotid systolic pressures
| Hemodynamic | Total sample (n=3,762) | Non-medicated (n=1,204) | ||||
|---|---|---|---|---|---|---|
| Parameter | Coef. (SE) |
Partial R2 | P-value | Coef. (SE) |
Partial R2 | P-value |
| Brachial systolic pressure | ||||||
| cfPWV | 0.02 (0.0009) |
0.134 | <0.0001 | 0.02 (0.002) |
0.121 | <0.0001 |
| SV index | 1.71 (0.30) |
0.009 | <0.0001 | 1.80 (0.50) |
0.011 | 0.0004 |
| AI | 4.50 (0.29) |
0.067 | <0.0001 | 4.17 (0.49) |
0.060 | <0.0001 |
| LVEF | −0.05 (0.29) |
0.000009 | 0.86 | −0.66 (0.49) |
0.002 | 0.18 |
| ET | 3.37 (0.28) |
0.040 | <0.0001 | 2.35 (0.51) |
0.017 | <0.0001 |
| UT | −2.15 (0.28) |
0.016 | <0.0001 | −2.25 (0.50) |
0.017 | <0.0001 |
|
| ||||||
| Carotid systolic pressure | ||||||
| cfPWV | 0.02 (0.001) |
0.089 | <0.0001 | 0.02 (0.002) |
0.091 | <0.0001 |
| SV index | 2.97 (0.38) |
0.016 | <0.0001 | 2.65 (0.63) |
0.014 | <0.0001 |
| AI | 4.83 (0.37) |
0.045 | <0.0001 | 4.22 (0.62) |
0.039 | <0.0001 |
| LVEF | 0.70 (0.36) |
0.001 | 0.05 | 0.11 (0.61) |
0.00003 | 0.86 |
| ET | 5.94 (0.34) |
0.072 | <0.0001 | 4.53 (0.63) |
0.040 | <0.0001 |
| UT | −2.35 (0.36) |
0.011 | <0.0001 | −2.54 (0.62) |
0.014 | <0.0001 |
cfPWV=carotid-femoral pulse wave velocity, SV=stroke volume, LVEF=left ventricular ejection fraction, AI=augmentation index, ET=ejection time, UT=upstroke time.
All analyses were adjusted for age, sex, black race, BMI, diabetes, and current smoking status. Coefficients represent change in systolic pressure per 1-SD change in the hemodynamic parameter.