Figure 1.
Summary of input parameters for the pharmacokinetic model used in the development of the digital reference object (DRO). The population-based arterial input function (AIF) was computed from 23 glioblastomas (A). The paired distribution of cerebral blood volume (CBV) and cerebral blood flow (CBF) was derived from the same database and scaled by dynamic computed tomography (CT) perfusion data (B). The distribution of Ktrans was derived from previously published dynamic CT perfusion data (C).