Biomaterial structures dictate important parameters including degradation and controlled release of therapeutics. The architecture, shown by scanning electron micrographs, varies among hydrogels, such as (A) keratin, (B) porcine-derived skeletal muscle ECM, (C) porcine-derived pericardial ECM, (D) collagen, (E) alginate, or (F) fibrin. Additionally, hydrogel architecture differs from particles like (G) poly(lactic-co-glycolic acid) microparticles or (H) acetalated dextran microparticles. Reproduced with permission from (49,55,61,88,91–93):
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