Comparison 2.

Medication versus medication: brimonidine versus apraclonidine (regardless of timing)

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Intraocular pressure (IOP) increase of ≥ 5 mmHg within 2 hours after laser trabeculoplasty (LTP)	2	71	Risk Ratio (M-H, Random, 95% CI)	2.28 [0.32, 16.03]
2 Mean change in IOP from pre-LTP to measurements taken within 2 hours after LTP (mmHg)	2	71	Mean Difference (IV, Random, 95% CI)	−0.69 [−2.56, 1.17]